مجله آب و فاضلاب

مجله آب و فاضلاب

حذف فتوکاتالیستی داروی دوکسوروبیسین از محلول آبی با استفاده از فتوکاتالیست پلیمر با ساختار آلی-کووالانسی تریازین تحت نور مرئی

نوع مقاله : مقاله پژوهشی

نویسندگان
سیدمحمد امیر شاه کرمی 1
سهیل سبحان اردکانی 2
مهرداد چراغی 2
بهاره لرستانی 2
عاطفه چمنی 3
1 دانشجوی دکترای تخصصی مهندسی محیط‌زیست، گروه مهندسی محیط‌زیست، واحد همدان، دانشگاه آزاد اسلامی، همدان، ایران
2 استاد، گروه محیط‌زیست، واحد همدان، دانشگاه آزاد اسلامی، همدان، ایران
3 دانشیار، گروه محیط‌زیست، واحد اصفهان (خوراسگان)، دانشگاه آزاد اسلامی، اصفهان، ایران
10.22093/wwj.2025.521130.3490
چکیده
دوکسوروبیسین یک داروی ضد سرطان قوی است و وجود باقیمانده آن در فاضلاب می‌تواند اثرات مخربی بر محیط‌زیست و سلامت عمومی داشته باشد. این دارو، حتی در مقدار بسیار اندک نیز سمّی است و می‌تواند با اختلال در عملکرد طبیعی اکوسیستم‌های آبی، بر رشد، تولیدمثل و بقای انواع موجودات آبزی تأثیر منفی بگذارد. ازاین‌رو، این پژوهش با هدف بررسی کارایی حذف داروی دوکسوروبیسین از محیط‌های آبی با استفاده از فتوکاتالیست با ساختار آلی-کووالانسی تریازین تحت نور مرئی انجام شد. در این پژوهش، ابتدا فتوکاتالیست با ساختار آلی- کووالانسی تریازین به‌روش رفلاکس سنتز و کارایی آن در حذف دوکسوروبیسین بررسی شد. به‌منظور شناسایی فتوکاتالیست سنتز شده از آنالیزهای میکروسکوپ الکترونی عبوری، میکروسکوپ الکترونی روبشی، دستگاه پراش پرتو ایکس، آنالیز نقشه‌برداری عنصری، طیف‌سنجی مادون قرمز فوریه و طیف‌سنجی بازتابی نفوذی استفاده شد. همچنین، اثر متغیرهای pH معادل 3 تا 9، غلظت فتوکاتالیست 10 تا mg40 و زمان تماس 30 تا min120 نیز بر کارایی حذف دارو ارزیابی شد. یافته‌ها نشان داد که با افزایش زمان تماس تا min30، غلظت فتوکاتالیست تا mg40 و در pH برابر با 7، کارایی حذف دوکسوروبیسین تا 98 درصد افزایش یافت. مطالعه اسکاونجرها نیز نشان داد که اکسنده‌های ، e- و  نقش قابل‌توجهی در فرایند تخریب داروی دوکسوروبیسین از محلول آبی توسط COTP داشته‌اند. به‌طور کلی، پلیمر آلی- کووالانسی تریازین می‌تواند به‌عنوان یک فتوکاتالیست مؤثر برای حذف دوکسوروبیسین از پساب‌های دارویی تحت نور مرئی استفاده شود.
کلیدواژه‌ها
دوکسوروبیسین
پلیمر آلی- کووالانسی تریازین
تخریب فتوکاتالیستی
محلول آبی
نور مرئی

عنوان مقاله English

Photocatalytic Removal of Doxorubicin from Aqueous Solution Using a Covalent Organic Triazine Polymer under Visible Light

نویسندگان English

Seyed Mohammad Amir Shah Karami 1
Soheil Sobhan Ardakani 2
Mehrdad Cheraghi 2
Bahareh Lorestani 2
Atefeh Chamani 3
1 PhD. Candidate, Dept. of the Environmental Engineering, Hamedan Branch, Islamic Azad University, Hamedan, Iran
2 Prof., Dept. of the Environment, Hamedan Branch, Islamic Azad University, Hamedan, Iran
3 Assoc. Prof., Dept. of the Environment, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
چکیده English

Doxorubicin is a potent anti-cancer drug, and its presence in wastewater may pose harmful effects l effects on the environment and public health. Even at very low doses, this drug is toxic and can disrupt the natural functioning of aquatic ecosystems, negatively impacting the growth, reproduction, and survival of various aquatic organisms. Therefore, this study was conducted to investigate the effectiveness of removing doxorubicin from aquatic environments using a covalent organic triazine polymer-based photocatalyst under visible light. In this research, a photocatalyst based on a covalent organic triazine polymer was first synthesized via a reflux method, and its efficiency in removing doxorubicin was examined. To characterize the synthesized photocatalyst, analyses including transmission electron microscopy, scanning electron microscopy, x-ray diffraction, energy dispersive x-ray mapping, fourier transform infrared spectroscopy and diffuse reflectance spectroscopy were performed. Additionally, the effects of variables such as pH (3-9), photocatalyst concentration (10-40 mg), and contact time (30-120 minutes) on the removal efficiency of doxorubicin were evaluated. The findings showed that the removal efficiency of doxorubicin was 98% at contact time of 30 min, with photocatalyst concentration of 40 mg, and pH = 7. The scavenger study revealed that oxidants such as , e and  played a significant role in the degradation process of doxorubicin in aqueous solution by COTP. The results demonstrated that the covalent organic triazine polymer can serve as an effective photocatalyst for removing doxorubicin from pharmaceutical wastewater under visible light.

کلیدواژه‌ها English

Doxorubicin
Covalent Organic Triazine Polymer
Photocatalytic Degradation
Aqueous Solution
Visible Light
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مجله آب و فاضلاب
دوره 36، شماره 1 - شماره پیاپی 156
فروردین و اردیبهشت 1404
صفحه 58-73